fusioncatcher-json
"fusionCatcher":[
{
"genes":{
"first":{
"hgnc":"ETV6",
"isOncogene":true
},
"second":{
"hgnc":"RUNX1"
},
"isParalogPair":true,
"isPseudogenePair":true,
"isReadthrough":true
},
"germlineSources":[
"1000 Genomes Project"
],
"somaticSources":[
"COSMIC",
"TCGA oesophageal carcinomas"
]
}
]
Field | Type | Notes |
---|---|---|
genes | genes object | 5' gene & 3' gene |
germlineSources | string array | matches in known germline data sources |
somaticSources | string array | matches in known somatic data sources |
genes
Field | Type | Notes |
---|---|---|
first | gene object | 5' gene |
second | gene object | 3' gene |
isParalogPair | bool | true when both genes are paralogs for each other |
isPseudogenePair | bool | true when both genes are pseudogenes for each other |
isReadthrough | bool | true when this fusion gene is a readthrough event (both are on the same strand and there are no genes between them) |
gene
Field | Type | Notes |
---|---|---|
hgnc | string | gene symbol. e.g. MSH6 |
isOncogene | bool | true when this gene is an oncogene |